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NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance
Axon pathfinding is critical for nervous system development, and it is orchestrated by molecular cues that activate receptors on the axonal growth cone. Robo family receptors bind Slit guidance cues to mediate axon repulsion. In mammals, the divergent family member Robo3 does not bind Slits, but ins...
Uloženo v:
| Vydáno v: | Nat Commun |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7083938/ https://ncbi.nlm.nih.gov/pubmed/32198364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15211-1 |
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