Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity

Tumour cell phagocytosis by antigen presenting cells (APCs) is critical to the generation of antitumour immunity. However, cancer cells can evade phagocytosis by upregulating anti-phagocytosis molecule CD47. Here, we show that CD47 blockade alone is inefficient in stimulating glioma cell phagocytosi...

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發表在:Nat Commun
Main Authors: von Roemeling, Christina A., Wang, Yifan, Qie, Yaqing, Yuan, Hengfeng, Zhao, Hai, Liu, Xiujie, Yang, Zhaogang, Yang, Mingming, Deng, Weiye, Bruno, Katelyn A., Chan, Charles K., Lee, Andrew S., Rosenfeld, Stephen S., Yun, Kyuson, Johnson, Aaron J., Mitchell, Duane A., Jiang, Wen, Kim, Betty Y. S.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083893/
https://ncbi.nlm.nih.gov/pubmed/32198351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15129-8
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