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Iron dyshomeostasis, lipid peroxidation and perturbed expression of cystine/glutamate antiporter in Alzheimer’s disease: Evidence of ferroptosis

Iron dyshomeostasis is implicated in Alzheimer’s disease (AD) alongside β-amyloid and tau pathologies. Despite the recent discovery of ferroptosis, an iron-dependent form cell death, hitherto, in vivo evidence of ferroptosis in AD is lacking. The present study uniquely adopts an integrated multi-dis...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Ashraf, Azhaar, Jeandriens, Jérôme, Parkes, Harold G., So, Po-Wah
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083890/
https://ncbi.nlm.nih.gov/pubmed/32199332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101494
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