Lipid analogs reveal features critical for hemolysis and diminish granadaene mediated Group B Streptococcus infection

Although certain microbial lipids are toxins, the structural features important for cytotoxicity remain unknown. Increased functional understanding is essential for developing therapeutics against toxic microbial lipids. Group B Streptococci (GBS) are bacteria associated with preterm births, stillbi...

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Publicado en:Nat Commun
Autores principales: Armistead, Blair, Herrero-Foncubierta, Pilar, Coleman, Michelle, Quach, Phoenicia, Whidbey, Christopher, Justicia, Jose, Tapia, Ruben, Casares, Raquel, Millán, Alba, Haidour, Ali, Granger, Javier Rodriguez, Vornhagen, Jay, Santana-Ufret, Verónica, Merillat, Sean, Adams Waldorf, Kristina, Cuerva, Juan Manuel, Rajagopal, Lakshmi
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083881/
https://ncbi.nlm.nih.gov/pubmed/32198389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15282-0
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