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Extrapolating Antifungal Animal Data to Humans – Is it reliable?

PURPOSE OF REVIEW: This article aimed to review animal models of antifungals and identifies human literature to assess if the extrapolation of results is reliable. RECENT FINDINGS: Animal studies have helped identify AUC/MIC targets for new drugs and formulations such as isavuconazole and delayed re...

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Detalhes bibliográficos
Publicado no:Curr Fungal Infect Rep
Main Authors: Stevens, Victoria M, Mueller, Scott W, Reynolds, Paul M, MacLaren, Robert, Kiser, Tyree H
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083583/
https://ncbi.nlm.nih.gov/pubmed/32201545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12281-020-00370-x
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