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Interneuron Transplantation Rescues Social Behavior Deficits without Restoring Wild-Type Physiology in a Mouse Model of Autism with Excessive Synaptic Inhibition
Manipulations that enhance GABAergic inhibition have been associated with improved behavioral phenotypes in autism models, suggesting that autism may be treated by correcting underlying deficits of inhibition. Interneuron transplantation is a method for increasing recipient synaptic inhibition, and...
שמור ב:
| הוצא לאור ב: | J Neurosci |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Society for Neuroscience
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7083289/ https://ncbi.nlm.nih.gov/pubmed/31988060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1063-19.2019 |
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