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Hardy-Weinberg Equilibrium in the Large Scale Genomic Sequencing Era
Hardy-Weinberg Equilibrium (HWE) is used to estimate the number of homozygous and heterozygous variant carriers based on its allele frequency in populations that are not evolving. Deviations from HWE in large population databases have been used to detect genotyping errors, which can result in extrem...
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| Publicado no: | Front Genet |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7083100/ https://ncbi.nlm.nih.gov/pubmed/32231685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00210 |
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