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Advances and challenges in rational drug design for SLCs
There are over 420 human Solute Carrier transporters (SLCs) from 65 families that are expressed ubiquitously in the body. The SLCs mediate the movement of ions, drugs, and metabolites across membranes, and their dysfunction has been associated with a variety of diseases, such as diabetes, cancer, an...
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| Veröffentlicht in: | Trends Pharmacol Sci |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7082830/ https://ncbi.nlm.nih.gov/pubmed/31519459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2019.08.006 |
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