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Advances and challenges in rational drug design for SLCs

There are over 420 human Solute Carrier transporters (SLCs) from 65 families that are expressed ubiquitously in the body. The SLCs mediate the movement of ions, drugs, and metabolites across membranes, and their dysfunction has been associated with a variety of diseases, such as diabetes, cancer, an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Trends Pharmacol Sci
Egile Nagusiak: Garibsingh, Rachel-Ann A, Schlessinger, Avner
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082830/
https://ncbi.nlm.nih.gov/pubmed/31519459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2019.08.006
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