Pathophysiological Mechanisms and Potential Therapeutic Targets in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL)

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), is a hereditary small-vessels angiopathy caused by mutations in the NOTCH 3 gene, located on chromosome 19, usually affecting middle-ages adults, whose clinical manifestations include migraine with...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Locatelli, Martina, Padovani, Alessandro, Pezzini, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082755/
https://ncbi.nlm.nih.gov/pubmed/32231578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00321
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