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Hazards of Using Masking Protocols When Performing Ligand Binding Assays: Lessons From the Sigma-1 and Sigma-2 Receptors

Sigma-1 and sigma-2 receptors are emerging therapeutic targets. Although the molecular identity of the sigma-2 receptor has recently been determined, receptor quantitation has used, and continues to use, the sigma-1 selective agents (+) pentazocine or dextrallorphan to mask the sigma-1 receptor in r...

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Bibliografiska uppgifter
I publikationen:Front Pharmacol
Huvudupphovsmän: Abbas, Haider, Borde, Preeti, Willars, Gary B., Ferry, David R., Safrany, Stephen T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082753/
https://ncbi.nlm.nih.gov/pubmed/32231573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00309
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