Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars

OBJECTIVE: Nonalcoholic fatty liver disease (i.e., increased intrahepatic triglyceride [IHTG] content), predisposes to type 2 diabetes and cardiovascular disease. Adipose tissue lipolysis and hepatic de novo lipogenesis (DNL) are the main pathways contributing to IHTG. We hypothesized that dietary m...

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Detalhes bibliográficos
Publicado no:Diabetes Care
Main Authors: Luukkonen, Panu K., Sädevirta, Sanja, Zhou, You, Kayser, Brandon, Ali, Ashfaq, Ahonen, Linda, Lallukka, Susanna, Pelloux, Véronique, Gaggini, Melania, Jian, Ching, Hakkarainen, Antti, Lundbom, Nina, Gylling, Helena, Salonen, Anne, Orešič, Matej, Hyötyläinen, Tuulia, Orho-Melander, Marju, Rissanen, Aila, Gastaldelli, Amalia, Clément, Karine, Hodson, Leanne, Yki-Järvinen, Hannele
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2018
Assuntos:
Pathophysiology/Complications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082640/
https://ncbi.nlm.nih.gov/pubmed/29844096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc18-0071
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