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The Red Blood Cell—Inflammation Vicious Circle in Sickle Cell Disease
Sickle cell disease (SCD) is a genetic disease caused by a single mutation in the β-globin gene, leading to the production of an abnormal hemoglobin called hemoglobin S (HbS), which polymerizes under deoxygenation, and induces the sickling of red blood cells (RBCs). Sickled RBCs are very fragile and...
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| Publicado no: | Front Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7082402/ https://ncbi.nlm.nih.gov/pubmed/32231672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00454 |
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