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Rechallenge with erlotinib in osimertinib-resistant lung adenocarcinoma mediated by driver gene loss: a case report

The efficacy and safety of osimertinib have been demonstrated in several clinical trials; however, acquired resistance is an inevitable problem associated with most targeted drugs. Based on previous findings, the mechanism of osimertinib resistance is equivocal, and there is still no consensus on th...

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Publicat a:Transl Lung Cancer Res
Autors principals: Liu, Lingli, Lizaso, Analyn, Mao, Xinru, Yang, Nong, Zhang, Yongchang
Format: Artigo
Idioma:Inglês
Publicat: AME Publishing Company 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082283/
https://ncbi.nlm.nih.gov/pubmed/32206561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr.2020.01.10
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