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BRCA1 and S Phase DNA Repair Pathways Restrict LINE-1 Retrotransposition in Human Cells
Long interspersed element-1 (LINE-1 or L1) is the only autonomous retrotransposon active in human cells. Different host factors have been shown to influence L1 mobility however, systematic analyses of these factors are limited. Here, we developed a high-throughput microscopy-based retrotransposition...
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| Publicado no: | Nat Struct Mol Biol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7082080/ https://ncbi.nlm.nih.gov/pubmed/32042152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0374-z |
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