Genetic Variability of Long Terminal Repeat Region between HIV-2 Groups Impacts Transcriptional Activity

The HIV-2 long terminal repeat (LTR) region contains several transcription factor (TF) binding sites. Efficient LTR transactivation by cellular TF and viral proteins is crucial for HIV-2 reactivation and viral production. Proviral LTRs from 66 antiretroviral-naive HIV-2-infected patients included in...

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Vydáno v:J Virol
Hlavní autoři: Le Hingrat, Quentin, Visseaux, Benoit, Bertine, Mélanie, Chauveau, Lise, Schwartz, Olivier, Collin, Fidéline, Damond, Florence, Matheron, Sophie, Descamps, Diane, Charpentier, Charlotte
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081896/
https://ncbi.nlm.nih.gov/pubmed/31915276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01504-19
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