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EPIGENETIC BASIS FOR ABDOMINAL AORTIC VASCULAR SMOOTH MUSCLE ADAPTATION TO PREGNANCY

BACKGROUND/AIMS: Ten-Eleven-Translocation (Tet), a DNA demethylase enzyme, has been identified as a master epigenetic regulator of vascular smooth muscle cell plasticity that could alter the biomechanics of the pregnant aorta. We hypothesized that pregnancy will induce significant adaptive changes i...

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Pubblicato in:J Vasc Res
Autori principali: Gelinne, Aaron, Brown, Lucia, Ko, Nga Ling, Osol, George, Brown, Stephen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081772/
https://ncbi.nlm.nih.gov/pubmed/30347403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000493682
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