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Comparative analysis of dose-dependent neurotoxic response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 N mice derived from three different sources

MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is commonly used to induce nigrostriatal defects to induce parkinsonism and/or parkinsonian syndrome, to replicate the lesions seen in Parkinson’s disease (PD), with use in numerous PD models in mice. It has been suggested that various biological ch...

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Detalhes bibliográficos
Publicado no:Lab Anim Res
Main Authors: Hwang, Dong-Joo, Kwon, Ki-Chun, Song, Hyun-Keun, Kim, Kil-Soo, Jung, Young-Suk, Hwang, Dae-Youn, Cho, Joon-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081672/
https://ncbi.nlm.nih.gov/pubmed/32257898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s42826-019-0012-2
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