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Optimization of small RNA library preparation protocol from human urinary exosomes

BACKGROUND: Sequencing of miRNAs isolated from exosomes has great potential to identify novel disease biomarkers, but exosomes have low amount of RNA, hindering adequate analysis and quantification. Here, we have assessed several steps in developing an optimized small RNA (sRNA) library preparation...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Olivares, Dolores, Perez-Hernandez, Javier, Perez-Gil, Daniel, Chaves, Felipe J., Redon, Josep, Cortes, Raquel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081560/
https://ncbi.nlm.nih.gov/pubmed/32188466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02298-9
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