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Tumor fitness, immune exhaustion and clinical outcomes: impact of immune checkpoint inhibitors

Recently proposed tumor fitness measures, based on profiling neoepitopes for reactive viral epitope similarity, have been proposed to predict response to immune checkpoint inhibitors in melanoma and small-cell lung cancer. Here we applied these checkpoint based fitness measures to the matched checkp...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bubie, Adrian, Gonzalez-Kozlova, Edgar, Akers, Nicholas, Villanueva, Augusto, Losic, Bojan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081289/
https://ncbi.nlm.nih.gov/pubmed/32193450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61992-2
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