Identification of Novel Alzheimer’s Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data

With the advent of whole genome-sequencing (WGS) studies, family-based designs enable sex-specific analysis approaches that can be applied to only affected individuals; tests using family-based designs are attractive because they are completely robust against the effects of population substructure....

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Publicado no:Sci Rep
Main Authors: Prokopenko, Dmitry, Hecker, Julian, Kirchner, Rory, Chapman, Brad A., Hoffman, Oliver, Mullin, Kristina, Hide, Winston, Bertram, Lars, Laird, Nan, DeMeo, Dawn L., Lange, Christoph, Tanzi, Rudolph E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081222/
https://ncbi.nlm.nih.gov/pubmed/32193444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61883-6
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