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Sensitivity-enhanced three-dimensional and carbon-detected two-dimensional NMR of proteins using hyperpolarized water

Signal enhancements of up to two orders of magnitude in protein NMR can be achieved by employing HDO as a vector to introduce hyperpolarization into folded or intrinsically disordered proteins. In this approach, hyperpolarized HDO produced by dissolution-dynamic nuclear polarization (D-DNP) is mixed...

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Bibliografiske detaljer
Udgivet i:J Biomol NMR
Main Authors: Olsen, Gregory L., Szekely, Or, Mateos, Borja, Kadeřávek, Pavel, Ferrage, Fabien, Konrat, Robert, Pierattelli, Roberta, Felli, Isabella C., Bodenhausen, Geoffrey, Kurzbach, Dennis, Frydman, Lucio
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080779/
https://ncbi.nlm.nih.gov/pubmed/32040802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-020-00301-5
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