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Mechanisms of Anthracycline-Induced Cardiotoxicity: Is Mitochondrial Dysfunction the Answer?

Cardiac side effects are a major drawback of anticancer therapies, often requiring the use of low and less effective doses or even discontinuation of the drug. Among all the drugs known to cause severe cardiotoxicity are anthracyclines that, though being the oldest chemotherapeutic drugs, are still...

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Опубликовано в: :Front Cardiovasc Med
Главные авторы: Murabito, Alessandra, Hirsch, Emilio, Ghigo, Alessandra
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080657/
https://ncbi.nlm.nih.gov/pubmed/32226791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2020.00035
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