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Chronic alcohol disrupts hypothalamic responses to stress by modifying CRF and NMDA receptor function

The chronic inability of alcoholics to effectively cope with relapse-inducing stressors has been linked to dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis and corticotropin-releasing factor (CRF) signaling. However, the cellular mechanisms responsible for this dysregulation are yet to...

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Bibliographic Details
Published in:Neuropharmacology
Main Authors: Marty, Vincent N., Mulpuri, Yatendra, Munier, Joseph J., Spigelman, Igor
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080583/
https://ncbi.nlm.nih.gov/pubmed/32059962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2020.107991
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