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Ataxia telangiectasia mutated pathway disruption affects hepatic DNA and tissue damage in nonalcoholic fatty liver disease

To overcome the rising burdens of nonalcoholic fatty liver disease, mechanistic linkages in mitochondrial dysfunction, inflammation and hepatic injury are critical. As ataxia telangiectasia mutated (ATM) gene oversees DNA integrity and mitochondrial homeostasis, we analyzed mRNAs and total proteins...

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Detalhes bibliográficos
Publicado no:Exp Mol Pathol
Main Authors: Viswanathan, Preeti, Sharma, Yogeshwar, Maisuradze, Luka, Tchaikovskaya, Tatyana, Gupta, Sanjeev
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080576/
https://ncbi.nlm.nih.gov/pubmed/31917286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2020.104369
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