Modeling Tumor Growth and Treatment Resistance Dynamics Characterizes Different Response to Gefitinib or Chemotherapy in Non‐Small Cell Lung Cancer

Differences in the effect of gefitinib and chemotherapy on tumor burden in non‐small cell lung cancer remain to be fully understood. Using a Bayesian hierarchical model of tumor size dynamics, we estimated the rates of tumor growth and treatment resistance for patients in the Iressa Pan‐Asia Study s...

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Veröffentlicht in:CPT Pharmacometrics Syst Pharmacol
Hauptverfasser: Nagase, Mario, Aksenov, Sergey, Yan, Hong, Dunyak, James, Al‐Huniti, Nidal
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080537/
https://ncbi.nlm.nih.gov/pubmed/31920008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12490
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