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The novel amidocarbamate derivatives of ketoprofen: synthesis and biological activity

A series of novel ketoprofen derivatives 4a–j bearing both amide and carbamate functionalities were prepared using the benzotriazole method of carboxylic and hydroxy group activation. Selective reduction of ketoprofen produced hydroxy derivative 2, which in the reaction with one or two moles of 1-be...

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Detalhes bibliográficos
Publicado no:Med Chem Res
Main Authors: Rajić, Zrinka, Hadjipavlou-Litina, Dimitra, Pontiki, Eleni, Balzarini, Jan, Zorc, Branka
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079954/
https://ncbi.nlm.nih.gov/pubmed/32214761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-010-9309-2
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