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Enhanced induction of dendritic cell maturation and HLA-A*0201-restricted CEA-specific CD8(+) CTL response by exosomes derived from IL-18 gene-modified CEA-positive tumor cells

Dendritic cells (DC)-derived or tumor-derived exosomes are a population of nanometer sized membrane vesicles that can induce specific anti-tumor immunity. However, the immunogenic potential and efficiency of exosomes-based tumor vaccine are not satisfactory enough to achieve a curative effect in cli...

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Detalhes bibliográficos
Publicado no:J Mol Med (Berl)
Main Authors: Dai, Shengming, Zhou, Xiangyang, Wang, Baomei, Wang, Qingqing, Fu, Yangxin, Chen, Taoyong, Wan, Tao, Yu, Yizhi, Cao, Xuetao
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079873/
https://ncbi.nlm.nih.gov/pubmed/17016692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-006-0102-0
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