A New Selective Pharmacological Enhancer of the Orai1 Ca(2+) Channel Reveals Roles for Orai1 in Smooth and Skeletal Muscle Functions

[Image: see text] Store-operated calcium (Ca(2+)) entry is an important homeostatic mechanism in cells, whereby the release of Ca(2+) from intracellular endoplasmic reticulum stores triggers the activation of a Ca(2+) influx pathway. Mediated by Orai1, this Ca(2+) influx has specific and essential r...

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書誌詳細
出版年:ACS Pharmacol Transl Sci
主要な著者: Azimi, Iman, Stevenson, Ralph J., Zhang, Xuexin, Meizoso-Huesca, Aldo, Xin, Ping, Johnson, Martin, Flanagan, Jack U., Chalmers, Silke B., Yoast, Ryan E., Kapure, Jeevak S., Ross, Benjamin P., Vetter, Irina, Ashton, Mark R., Launikonis, Bradley S., Denny, William A., Trebak, Mohamed, Monteith, Gregory R.
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2020
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079732/
https://ncbi.nlm.nih.gov/pubmed/32190822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00081
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