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PESM: predicting the essentiality of miRNAs based on gradient boosting machines and sequences

BACKGROUND: MicroRNAs (miRNAs) are a kind of small noncoding RNA molecules that are direct posttranscriptional regulations of mRNA targets. Studies have indicated that miRNAs play key roles in complex diseases by taking part in many biological processes, such as cell growth, cell death and so on. Th...

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Библиографические подробности
Опубликовано в: :BMC Bioinformatics
Главные авторы: Yan, Cheng, Wu, Fang-Xiang, Wang, Jianxin, Duan, Guihua
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079416/
https://ncbi.nlm.nih.gov/pubmed/32183740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3426-9
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