Aptamer-Functionalized Fibrin Hydrogel Improves Vascular Endothelial Growth Factor Release Kinetics and Enhances Angiogenesis and Osteogenesis in Critically Sized Cranial Defects

An aging population, decreased activity levels and increased combat injuries, have led to an increase in critical sized bone defects. As more defects are treated using allografts, which is the current standard of care, the deficiencies of allografts are becoming more evident. Allografts lack the ang...

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Detalhes bibliográficos
Publicado no:ACS Biomater Sci Eng
Main Authors: Juhl, Otto, Zhao, Nan, Merife, Anna-Blessing, Cohen, David, Friedman, Michael, Zhang, Yue, Schwartz, Zvi, Wang, Yong, Donahue, Henry
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079287/
https://ncbi.nlm.nih.gov/pubmed/32190730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsbiomaterials.9b01175
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