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Acid‐Cleavable Poly(ethylene glycol) Hydrogels Displaying Protein Release at pH 5

PEG is the gold standard polymer for pharmaceutical applications, however it lacks degradability. Degradation under physiologically relevant pH as present in endolysosomes, cancerous and inflammatory tissues is crucial for many areas. The authors present anionic ring‐opening copolymerization of ethy...

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Publicat a:Chemistry
Autors principals: Ewald, Johannes, Blankenburg, Jan, Worm, Matthias, Besch, Laura, Unger, Ronald E., Tremel, Wolfgang, Frey, Holger, Pohlit, Hannah
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079179/
https://ncbi.nlm.nih.gov/pubmed/31850549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201905310
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