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Next generation oncology drug development: opportunities and challenges
The optimal development of novel molecularly targeted agents for the treatment of cancer requires a re-evaluation of the current drug development paradigm. selection of patients, optimal biologic dose versus maximum tolerated dose, definition of response and clinical benefit and trial designs that a...
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| Publicado no: | Nat Rev Clin Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7079165/ https://ncbi.nlm.nih.gov/pubmed/19390552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2009.38 |
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