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S100 Soil Sensor Receptors and Molecular Targeting Therapy Against Them in Cancer Metastasis
The molecular mechanisms underlying the ‘seed and soil’ theory are unknown. S100A8/A9 (a heterodimer complex of S100A8 and S100A9 proteins that exhibits a ‘soil signal’) is a ligand for Toll-like receptor 4, causing distant melanoma cells to approach the lung as a ‘seeding’ site. Unknown soil sensor...
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| Udgivet i: | Transl Oncol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Neoplasia Press
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7078545/ https://ncbi.nlm.nih.gov/pubmed/32193075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100753 |
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