Long Noncoding RNA H19 Impairs the Intestinal Barrier by Suppressing Autophagy and Lowering Paneth and Goblet Cell Function

BACKGROUND & AIMS: The protective intestinal mucosal barrier consists of multiple elements including mucus and epithelial layers and immune defense; nonetheless, barrier dysfunction is common in various disorders. The imprinted and developmentally regulated long noncoding RNA H19 is involved in...

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Vydáno v:Cell Mol Gastroenterol Hepatol
Hlavní autoři: Yu, Ting-Xi, Chung, Hee K., Xiao, Lan, Piao, Jun-Jie, Lan, Shaoyang, Jaladanki, Suraj K., Turner, Douglas J., Raufman, Jean-Pierre, Gorospe, Myriam, Wang, Jian-Ying
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078540/
https://ncbi.nlm.nih.gov/pubmed/31862317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2019.12.002
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