Gamma Interferon Is Required for Chlamydia Clearance but Is Dispensable for T Cell Homing to the Genital Tract

While there is no effective vaccine against Chlamydia trachomatis infection, previous work has demonstrated the importance of C. trachomatis-specific CD4(+) T cells (NR1 T cells) in pathogen clearance. Specifically, NR1 T cells have been shown to be protective in mice, and this protection depends on...

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Bibliographic Details
Published in:mBio
Main Authors: Helble, Jennifer D., Gonzalez, Rodrigo J., von Andrian, Ulrich H., Starnbach, Michael N.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078466/
https://ncbi.nlm.nih.gov/pubmed/32184237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00191-20
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