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Comparative Pathology of Human and Canine Myxomatous Mitral Valve Degeneration: 5HT and TGF-β Mechanisms

Myxomatous mitral valve degeneration (MMVD) is a leading cause of valve repair or replacement secondary to the production of mitral regurgitation, cardiac enlargement, systolic dysfunction, and heart failure. The pathophysiology of MMVD is complex and incompletely understood, but key features includ...

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Detalhes bibliográficos
Publicado no:Cardiovasc Pathol
Main Authors: Oyama, Mark A., Elliott, W. Chad, Loughran, Kerry A., Kossar, Alexander P., Castillero, Estibaliz, Levy, Robert J., Ferrari, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078050/
https://ncbi.nlm.nih.gov/pubmed/32006823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carpath.2019.107196
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