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Systematic re-evaluation of the long-used standard protocol of urease-dependent metabolome sample preparation

In the urinary metabolomics for finding biomarkers in urine, owing to high concentrations of urea, for chromatography-based metabolomic analysis, urea needed to be degraded by urease. This urease pretreatment has been the key step of sample preparation for standard urinary metabolomics until today e...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kim, Jungyeon, Ahn, Joong Kyong, Cheong, Yu Eun, Lee, Sung-Joon, Cha, Hoon-Suk, Kim, Kyoung Heon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077817/
https://ncbi.nlm.nih.gov/pubmed/32182259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230072
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