LPS‐induced inflammation desensitizes hepatocytes to Fas‐induced apoptosis through Stat3 activation—The effect can be reversed by ruxolitinib

Recent studies have established a concept of tumour necrosis factor‐α (TNF‐α)/Fas signalling crosstalk, highlighting TNF‐α as a critical cytokine in sensitizing hepatocytes to death induced by Fas activation. However, in the exact inflammatory response, besides TNF‐α, many other mediators, that migh...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Markotic, Antonio, Flegar, Darja, Grcevic, Danka, Sucur, Alan, Lalic, Hrvoje, Turcic, Petra, Kovacic, Natasa, Lukac, Nina, Pravdic, Danijel, Vukojevic, Katarina, Cavar, Ivan, Kelava, Tomislav
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077556/
https://ncbi.nlm.nih.gov/pubmed/32022429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14930
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