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Metformin upregulates mitophagy in patients with T2DM: A randomized placebo‐controlled study
Impaired mitochondrial autophagy (mitophagy) and NLRP3 inflammasome activation have been incriminated in the pathogenesis of T2DM. Metformin besides being an insulin sensitizer also induces autophagy; however, its effect on mitophagy and NLRP3 activation in patients with T2DM still remains elusive....
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| Publicado no: | J Cell Mol Med |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7077543/ https://ncbi.nlm.nih.gov/pubmed/31975558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14834 |
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