Comparison of CRISPR and Marker-Based Methods for the Engineering of Phage T7

With the recent rise in interest in using lytic bacteriophages as therapeutic agents, there is an urgent requirement to understand their fundamental biology to enable the engineering of their genomes. Current methods of phage engineering rely on homologous recombination, followed by a system of sele...

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Publicado no:Viruses
Principais autores: Grigonyte, Aurelija M., Harrison, Christian, MacDonald, Paul R., Montero-Blay, Ariadna, Tridgett, Matthew, Duncan, John, Sagona, Antonia P., Constantinidou, Chrystala, Jaramillo, Alfonso, Millard, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077284/
https://ncbi.nlm.nih.gov/pubmed/32050613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12020193
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