TSPphg Lysin from the Extremophilic Thermus Bacteriophage TSP4 as a Potential Antimicrobial Agent against Both Gram-Negative and Gram-Positive Pathogenic Bacteria

New strategies against antibiotic-resistant bacterial pathogens are urgently needed but are not within reach. Here, we present in vitro and in vivo antimicrobial activity of TSPphg, a novel phage lysin identified from extremophilic Thermus phage TSP4 by sequencing its whole genome. By breaking down...

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Publicat a:Viruses
Autors principals: Wang, Feng, Ji, Xinyu, Li, Qiupeng, Zhang, Guanling, Peng, Jiani, Hai, Jun, Zhang, Yao, Ci, Baiquan, Li, Hongwei, Xiong, Yan, Deng, Xianyu, Lin, Lianbing
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077265/
https://ncbi.nlm.nih.gov/pubmed/32050494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12020192
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