Antiviral Ranpirnase TMR-001 Inhibits Rabies Virus Release and Cell-to-Cell Infection In Vitro

Currently, no rabies virus-specific antiviral drugs are available. Ranpirnase has strong antitumor and antiviral properties associated with its ribonuclease activity. TMR-001, a proprietary bulk drug substance solution of ranpirnase, was evaluated against rabies virus in three cell types: mouse neur...

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Publicado en:Viruses
Main Authors: Smith, Todd G., Jackson, Felix R., Morgan, Clint N., Carson, William C., Martin, Brock E., Gallardo-Romero, Nadia, Ellison, James A., Greenberg, Lauren, Hodge, Thomas, Squiquera, Luis, Sulley, Jamie, Olson, Victoria A., Hutson, Christina L.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077210/
https://ncbi.nlm.nih.gov/pubmed/32033253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12020177
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