Transient Receptor Potential Channel Canonical Type 3 Deficiency Antagonizes Myofibroblast Transdifferentiation In Vivo

OBJECTIVE: Myofibroblast transformation has been shown to be associated with the reactive oxygen species- (ROS-) producing enzyme NADPH oxidase (Nox4). Inhibition of transient receptor potential channel canonical type 3 (TRPC3) attenuates mitochondrial calcium handling and ROS production in the vasc...

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Udgivet i:Biomed Res Int
Main Authors: Xia, Weijie, Wang, Qianran, Lu, Yuangang, Hu, Yingru, Zhang, Xingcun, Zhang, Junbo, Liu, Dongfang, Song, Jinlin, Zhu, Zhiming, Liu, Daoyan, Zhang, Hengshu
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077044/
https://ncbi.nlm.nih.gov/pubmed/32219126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/1202189
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