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MethylNet: an automated and modular deep learning approach for DNA methylation analysis

BACKGROUND: DNA methylation (DNAm) is an epigenetic regulator of gene expression programs that can be altered by environmental exposures, aging, and in pathogenesis. Traditional analyses that associate DNAm alterations with phenotypes suffer from multiple hypothesis testing and multi-collinearity du...

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Bibliografische gegevens
Gepubliceerd in:BMC Bioinformatics
Hoofdauteurs: Levy, Joshua J., Titus, Alexander J., Petersen, Curtis L., Chen, Youdinghuan, Salas, Lucas A., Christensen, Brock C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076991/
https://ncbi.nlm.nih.gov/pubmed/32183722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3443-8
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