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Curcumin, demethoxycurcumin, and bisdemethoxycurcumin induced caspase-dependent and –independent apoptosis via Smad or Akt signaling pathways in HOS cells

BACKGROUND: Osteosarcoma is the most common primary malignant bone tumor in children and adolescents and has also been associated with a high degree of malignancy and enhanced metastatic capacity. Curcumin (CUR) is well known for its anti-osteosarcoma activity. However, both demethoxycurcumin (DMC),...

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Bibliografske podrobnosti
izdano v:BMC Complement Med Ther
Main Authors: Huang, Cheng, Lu, Hsu-Feng, Chen, Yu-Hsuan, Chen, Jui-Chieh, Chou, Wen-Hsiang, Huang, Hsiu-Chen
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076840/
https://ncbi.nlm.nih.gov/pubmed/32126993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-020-2857-1
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