Once-weekly Somapacitan is Effective and Well Tolerated in Adults with GH Deficiency: A Randomized Phase 3 Trial

CONTEXT: Growth hormone (GH) replacement requires daily GH injections, which is burdensome for some adult patients with GH deficiency (AGHD). OBJECTIVE: To demonstrate efficacy and safety of somapacitan, a once-weekly reversible albumin-binding GH derivative, versus placebo in AGHD. DESIGN: Randomiz...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Endocrinol Metab
Prif Awduron: Johannsson, Gudmundur, Gordon, Murray B, Højby Rasmussen, Michael, Håkonsson, Ida Holme, Karges, Wolfram, Sværke, Claus, Tahara, Shigeyuki, Takano, Koji, Biller, Beverly M K
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Online Only Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076631/
https://ncbi.nlm.nih.gov/pubmed/32022863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgaa049
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