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Pharmacokinetics and Intestinal Metabolism of Compound K in Rats and Mice

We aimed to investigate the plasma concentration, tissue distribution, and elimination of compound K following the intravenous administration of compound K (2 mg/kg) in rats and mice. The plasma concentrations of compound K in mice were much higher (about five-fold) than those in rats. In both rats...

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Dades bibliogràfiques
Publicat a:Pharmaceutics
Autors principals: Jeon, Ji-Hyeon, Kang, Bitna, Lee, Sowon, Jin, Sojeong, Choi, Min-Koo, Song, Im-Sook
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076525/
https://ncbi.nlm.nih.gov/pubmed/32028741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12020129
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