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A Comparative Study of the Effect of Different Stabilizers on the Critical Quality Attributes of Self-Assembling Nano Co-Crystals

Lamivudine (3TC) and zidovudine (AZT) are antiviral agents used orally to manage HIV/AIDS infection. A pseudo one-solvent bottom-up approach was used to develop and produce nano co-crystals of 3TC and AZT. Equimolar amounts of 3TC dissolved in de-ionized water and AZT in methanol were rapidly inject...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Witika, Bwalya A., Smith, Vincent J., Walker, Roderick B.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076485/
https://ncbi.nlm.nih.gov/pubmed/32102162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12020182
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