Antagonizing binding of cell cycle and apoptosis regulatory protein 1 (CARP-1) to the NEMO/IKKγ protein enhances the anticancer effect of chemotherapy

NF-κB is a pro-inflammatory transcription factor that critically regulates immune responses and other distinct cellular pathways. However, many NF-κB–mediated pathways for cell survival and apoptosis signaling in cancer remain to be elucidated. Cell cycle and apoptosis regulatory protein 1 (CARP-1 o...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Principais autores: Venkatesh, Jaganathan, Sekhar, Sreeja C., Cheriyan, Vino T., Muthu, Magesh, Meister, Paul, Levi, Edi, Dzinic, Sijana, Gauld, James W., Polin, Lisa A., Rishi, Arun K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076213/
https://ncbi.nlm.nih.gov/pubmed/32024692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009898
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