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Functional analysis of Clostridium difficile sortase B reveals key residues for catalytic activity and substrate specificity
Most of Gram-positive bacteria anchor surface proteins to the peptidoglycan cell wall by sortase, a cysteine transpeptidase that targets proteins displaying a cell wall sorting signal. Unlike other bacteria, Clostridium difficile, the major human pathogen responsible for antibiotic-associated diarrh...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7076211/ https://ncbi.nlm.nih.gov/pubmed/32005667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011322 |
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